Page 159 - Programme book for The International Liver Congress 2015, EASL ILC 2015

Liver Tumours: Experimental

P0220 JNK SIGNALING ACTIVATED BY PLATELET-DERIVED
GROWTH FACTOR D (PDGF-D) STIMULATES SECRETION
OF VASCULAR ENDOTHELIAL GROWTH FACTOR-C
(VEGF-C) BY CANCER-ASSOCIATED FIBROBLASTS
TO PROMOTE LYMPHANGIOGENESIS AND EARLY
METASTASIZATION IN CHOLANGIOCARCINOMA
Massimiliano Cadamuro*, Marta Vismara, Simone Brivio,
Alberto Furlanetto, Mario Strazzabosco, Luca Fabris, Italy

P0221 ACQUIRED RESISTANCE TO SORAFENIB IN
HEPATOCELLULAR CARCINOMA IS MEDIATED BY TUMOR
INITIATING CELLS (CANCER STEM CELLS)
Victoria Tovar*, Helena Cornellà, Agrin Moeni, Samuel Vidal,
Yujin Hoshida, Daniela Sia, Judit Peix, Clara Alsinet, Iris M. Quetglas,
Manel Solé, Josep Domingo-Domenech, Augusto Villanueva,
Josep M. Llovet, Spain

P0222 RELEVANCE OF ORGANIC CATION TRANSPORTER OCT1
(SLC22A1) IN DIETHYLNITROSAMINE-INITIATED AND
PHENOBARBITAL-PROMOTED HEPATOCELLULAR ePOSTERS
CARCINOMA IN OCT3- KNOCKOUT MICE
Johanna Knapstein*, Peter Fuchs, Daniel Grimm, Anja Lautem,
Maria Hoppe-Lotichius, Marcus A. Woerns, Hauke Lang, Peter R. Galle,
Tim Zimmermann, Germany

P0223 ROLE OF ARL6IP5 IN HCV-RELATED HEPATOCELLULAR
CARCINOMA
Zenan Hu, George S. Wilson, Jacob George, Liang Qiao*, Australia

P0224 NINTEDANIB PREVENTS THE DEVELOPMENT OF
HEPATOCELLULAR CARCINOMA IN A MOUSE MODEL OF
FIBROSIS
Victoria Tovar*, Agrin Moeni, Sara Torrecilla, Monica Higuera, Judit Peix,
Iris M. Quetglas, Leonardo Rodriguez-Carunchio, Manel Solé,
Josep M. Llovet, Spain

Vienna, Austria • April 22–26, 2015 159