Page 236 - Programme book for The International Liver Congress 2015, EASL ILC 2015

Viral Hepatitis: Hepatitis C - Experimental (Virology)

P0671 MECHANISMS OF HCV-INDUCED DIABETES THROUGH
IMPAIRED INSULIN-DRIVEN GLUCONEOGENESIS SHUT-
DOWN BY HCV PROTEINS AS A RESULT OF UNCOUPLING
OF FOXO1/AKT SIGNALING
Hervé Lerat*, Jacqueline Polyte, Aurore Gaudin,
Mohamed-Rabah Imache, Christophe Magnan, Fabienne Foufelle,
Jean-Michel Pawlotsky, France

P0672 INTERACTION BETWEEN HEPATIC MEMBRANE TYPE-1
MATRIX METALLOPROTEINASE AND ACIREDUCTONE
DIOXYGENASE 1 REGULATES HEPATITIS C VIRUS
INFECTION
Chau-Ting Yeh*, Ju-Chien Cheng, Ming-Ling Chang, Taiwan

P0673 PATHOPHYSIOLOGY OF HCV-RELATED
HEPATOCELLULAR CARCINOMA: HCV PROTEIN
ePOSTERS EXPRESSION INDUCES THE ACTIVATION OF AKT1 IN
HEPATOCYTES THROUGH AN MTORC2 DEPENDENT
PATHWAY
Mohamed-Rabah Imache*, Jacqueline Polyte, Jean-Michel Pawlotsky,
Herve Lerat, France

P0674 CLINICALLY APPROVED T-TYPE CALCIUM CHANNEL
INHIBITORS PREVENT HEPATITIS C VIRUS (HCV)
MEMBRANE FUSION IN A GENOTYPE-DEPENDENT
MANNER
Paula M. Perin*, Sibylle Haid, Richard Brown, Kai Schulze,
Che C. Colpitts, Carsten Zeilinger, Markus von Schaewen,
Brigitte Heller, Koen Vercauteren, Eva Luxenburger,
Yasemine Andonyadis, Florian Vondran, Andreas Kirschning,
Luis M. Schang, Rolf Müller, Carlos A. Guzman, Lars Kaderali,
Glenn Randall, Philip Meuleman, Alexander Ploss, Thomas Pietschmann,
Germany

P0675 AN EXVIVO MODEL OF HUMAN LIVER SLICES CULTURE
FOR EVALUATING LIVER FIBROGENESIS
Sylvie Lagaye*, Jesintha Gaston, Jérôme Guéchot,
Pierre-Philippe Massault, Jean-Christophe Vaillant, Stanislas Pol, France

236 The International Liver Congress™ 2015 • ILC Programme