Page 238 - Programme book for The International Liver Congress 2015, EASL ILC 2015
P. 238
Viral Hepatitis: Hepatitis C - Experimental (Virology) (Cont.)
P0682 PRECLINICAL CHARACTERIZATION OF AL-335, A POTENT
URIDINE BASED NUCLEOSIDE POLYMERASE INHIBITOR
FOR THE TREATMENT OF CHRONIC HEPATITIS C
Hua Tan, Kenneth Shaw, Andreas Jekel, Jerome Deval, Zhinan Jin,
Amy Fung,Yuen Tam, Lawrence M. Blatt, Sushmita M. Chanda,
Guangyi Wang, Marjia Prhavc, Vladimir Serebryany, Qingling Zhang,
Julian A. Symons, Leonid Beigelman, David B. Smith*, The United States
P0683 HEPATITIS C VIRUS NS3-4A PROTEASE TARGETS THE
HOST FACTOR BNIP1 AT A NON-CANONICAL CLEAVAGE
SITE
Huong Thi Lan Tran, Kenichi Morikawa, François Penin,
Manfredo Quadroni, Jérôme Gouttenoire*, Darius Moradpour,
Switzerland
P0684 MODULATION OF HEPATITIS C VIRUS INFECTION
THROUGH KHSRP-DEPENDENT REGULATION OF
ePOSTERS MIRNA-122 MATURATION AND INTRACELLULAR RNA
DEGRADATION
Patrice Bruscella*, Hassan Danso, Camille Baudesson, Tony Durand,
Hélène Colman, Michel Ventura, Michele Trabucchi, Jean-
Michel Pawlotsky, Cyrille Féray, France
P0685 THE ROLE OF CAVEOLIN-1 IN THE PHENOTYPE OF
HUMAN T LYMPHOCYTES AFTER UPTAKE OF HCV NON-
ENVELOPED PARTICLES
Polyxeni P. Doumba*, Elisavet Serti, Maria Boutsikou,
Manousos M. Konstandoulakis, Urania Georgopoulou, John Koskinas,
Greece
P0686 RECIPROCAL ANTAGONISM BETWEEN THE
UNCOORDINATED PHENOTYPE-5A (UNC5A) DEPENDENCE
RECEPTOR AND THE HEPATITIS C VIRUS
Marie-Laure Plissonnier*, Thomas Lahlali, Maud Michelet,
Patrick Mehlen, Fabien Zoulim, Romain Parent, France
P0687 REGULATION OF HEPCIDIN (HAMP) AS DRIVING FORCE
FOR MACROPHAGE-MEDIATED HEPATITIS C (HCV)
PERSISTENCY
Pelagia Foka, Alexios Dimitriadis, Eirini Karamichali,
Eleni Kyratzopoulou, Dionyssios Giannimaras, John Koskinas,
Avgi Mamalaki, Urania Georgopoulou*, Greece
238 The International Liver Congress™ 2015 • ILC Programme
P0682 PRECLINICAL CHARACTERIZATION OF AL-335, A POTENT
URIDINE BASED NUCLEOSIDE POLYMERASE INHIBITOR
FOR THE TREATMENT OF CHRONIC HEPATITIS C
Hua Tan, Kenneth Shaw, Andreas Jekel, Jerome Deval, Zhinan Jin,
Amy Fung,Yuen Tam, Lawrence M. Blatt, Sushmita M. Chanda,
Guangyi Wang, Marjia Prhavc, Vladimir Serebryany, Qingling Zhang,
Julian A. Symons, Leonid Beigelman, David B. Smith*, The United States
P0683 HEPATITIS C VIRUS NS3-4A PROTEASE TARGETS THE
HOST FACTOR BNIP1 AT A NON-CANONICAL CLEAVAGE
SITE
Huong Thi Lan Tran, Kenichi Morikawa, François Penin,
Manfredo Quadroni, Jérôme Gouttenoire*, Darius Moradpour,
Switzerland
P0684 MODULATION OF HEPATITIS C VIRUS INFECTION
THROUGH KHSRP-DEPENDENT REGULATION OF
ePOSTERS MIRNA-122 MATURATION AND INTRACELLULAR RNA
DEGRADATION
Patrice Bruscella*, Hassan Danso, Camille Baudesson, Tony Durand,
Hélène Colman, Michel Ventura, Michele Trabucchi, Jean-
Michel Pawlotsky, Cyrille Féray, France
P0685 THE ROLE OF CAVEOLIN-1 IN THE PHENOTYPE OF
HUMAN T LYMPHOCYTES AFTER UPTAKE OF HCV NON-
ENVELOPED PARTICLES
Polyxeni P. Doumba*, Elisavet Serti, Maria Boutsikou,
Manousos M. Konstandoulakis, Urania Georgopoulou, John Koskinas,
Greece
P0686 RECIPROCAL ANTAGONISM BETWEEN THE
UNCOORDINATED PHENOTYPE-5A (UNC5A) DEPENDENCE
RECEPTOR AND THE HEPATITIS C VIRUS
Marie-Laure Plissonnier*, Thomas Lahlali, Maud Michelet,
Patrick Mehlen, Fabien Zoulim, Romain Parent, France
P0687 REGULATION OF HEPCIDIN (HAMP) AS DRIVING FORCE
FOR MACROPHAGE-MEDIATED HEPATITIS C (HCV)
PERSISTENCY
Pelagia Foka, Alexios Dimitriadis, Eirini Karamichali,
Eleni Kyratzopoulou, Dionyssios Giannimaras, John Koskinas,
Avgi Mamalaki, Urania Georgopoulou*, Greece
238 The International Liver Congress™ 2015 • ILC Programme
